The RITMS Center for Cellular Dynamics & Physics of Living Cells is transforming how we understand and treat disease. Guided by Dr. Steven An, a world-renowned leader in mechanobiology, the Center explores the hidden molecular forces that shape how our cells move, grow, and respond to their environment. These discoveries are more than scientific milestones—they hold the key to solving some of today’s most pressing health challenges, from asthma to cancer.
In lung biology, the Center has redefined our understanding of airway smooth muscle and its role in asthma. Beyond existing treatments, our researchers have uncovered an entirely new signaling pathway through sensory receptors—traditionally known for taste and smell—present on airway muscle cells. Activating these receptors produces powerful bronchodilation, opening a bold new path toward therapies that go beyond symptom relief to target the underlying causes of disease.